Tumors, especially hypernephroma; neoplastic ectopic production (Regan, Nagao isoenzymes). Joe Cohen flipped the script on conventional and alternative medicineand it worked. Elevated liver enzymes may indicate inflammation or damage to cells in the liver. Diagnosing and monitoring treatment of liver, bone, intestinal, and parathyroid diseases. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at support@selfdecode.com. Peptic ulcer, erosion. . You should not to eat or drink anything for 6 hours before the test, unless your health care provider tells you otherwise. Pediatric reference values should be used to properly interpret alkaline phosphatase values in children and adolescents. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. 2023 Laboratory Corporation of America Holdings. Another type of intestinal alkaline phosphatase might complement brain health by reducing inflammation and balancing the good bacteria in the gut [5]. Eating can interfere with your ALP levels. Serum alkaline phosphatase is a member of a family of zinc metalloprotein enzymes that function to split off a terminal phosphate group from an organic phosphate ester. Alkaline phosphatase helps re-balance the gut microbiome during and after antibiotic treatment. Healthline Media does not provide medical advice, diagnosis, or treatment. ISBN 9780721656106. Version 5.0.Published: November 27, 2017. Clin Chem Lab Med. Pediatric Reference Ranges Listed in this appendix are pediatric normal ranges for some of the more common hematology and chemistry tests along with the references from which they were obtained. In Paget disease of bone there is often isolated elevation of serum alkaline phosphatase. Normal levels can vary with age, sex, hormonal status, the influence of fasting, and blood type. . The enzyme interacts with the gut, the food we eat, and the microbes found in our body. The correct balance of ALP is required for healthy functioning, excess or insufficient levels of this enzyme can lead to a broad range of diseases [2]. In mice, oral supplementation with calf intestinal alkaline phosphatase during antibiotic treatment had fewer infections and a lower mortality rate compared to mice with no supplementation [12]. Increase tends to be more notable (greater than 4-fold the upper reference value [URV]) in extrahepatic obstruction (eg, by stone, by cancer of the head of the pancreas) than in intrahepatic obstruction and is greater the more complete the obstruction. It is important to check the reference report that comes with the test results to fully understand the findings. You may feel slight pain or a sting when the needle is inserted. Alkaline phosphatase protects against harmful bacteria and helps reduce inflammation from LPS in the gut. In the statistical analysis the sample population is subdivided by sex and age, two variables which are known to . Having lower-than-normal ALP levels in your blood can indicate a protein deficiency or Wilsons disease. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. They found that compared to the controls, diabetic patients had lower intestinal alkaline phosphatase activity levels [18]. Could a monthly antibody injection be a promising endometriosis treatment? (2021). . Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. American Association for Clinical Chemistry. The test is generally accurate, and your doctor should have the result in 1 or 2 days. If the results of the test are inconclusive, your doctor may order a follow-up test. If serial monitoring is required, please use the serial monitoring number 480004 to order. Normal values may vary slightly from . Testing schedules may vary. What causes a high level of ALP in a blood test? Normal bone is constantly undergoing remodeling in which bone degradation or resorption is balanced by bone formation. Recommendations on measurement units - why and how. Best in Northern CA is a clickable link to peer-reviewed scientific studies. Normal values may vary slightly from laboratory to laboratory. Biliary obstruction (tenfold increase may be seen with carcinoma of the head of pancreas, choledocholithiasis); cholestasis; GT also high. Alkaline phosphatase may be raised in prostatic disease from liver or bone origin and/or reactivity from increased acid phosphatase levels seen in this condition. ALP is most abundant in the liver and bones, and high ALP levels may stem from a health problem in these areas. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (kat/L). It is determined by measuring the increase in absorbance. Serum enzyme activities may reach 10 to 12 times the URV and usually return to baseline on surgical removal of the obstruction. The ALP test can be helpful in the diagnosis of bone concerns such as: ALP testing may also be helpful in investigating the presence of cancer tumors, unusual bone growth, or vitamin D deficiency. Drugs estrogens (large doses), birth control agents, methyltestosterone, phenothiazines, oral hypoglycemic agents, erythromycin, or any drug producing hypersensitivity or toxic cholestasis. Generally, the total alkaline phosphatase (ALP) test is run to find all types of ALP in the blood to diagnose bone and liver disorders. Marked decline of high ALP of pregnancy is seen with placental insufficiency and imminent fetal demise. ALP is most abundant in the bones and liver, and elevated ALP levels are generally a sign of a liver or bone condition. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, https://medlineplus.gov/lab-tests/alkaline-phosphatase/, https://www.testing.com/tests/alkaline-phosphatase-alp/, https://www.eatright.org/food/nutrition/healthy-eating/what-is-malnutrition, https://sites.kowsarpub.com/zjrms/articles/102994.html, https://www.ncbi.nlm.nih.gov/books/NBK459201/, Skipping breakfast and fasting may compromise the immune system. Enzymes are proteins that help chemical reactions happen. In rickets and osteomalacia, serum calcium and phosphorus are low to normal, and alkaline phosphatase may be normal or increased. Philadelphia, PA: Elsevier Saunders; 2016:chap 147. The activity of ALP found in serum is a composite of isoenzymes from those sites and, in some circumstances, placental or Regan isoenzymes. Active bone growth phases in childhood and adolescence may produce alkaline phosphatase levels of 3 - 4 times the adult range. Fatty metamorphosis of liver (moderate increase occurs in acute fatty liver). Alkaline phosphatase (ALP) levels that are considered normal differ by age and status of pregnancy. However, abnormal levels can also signify a severe medical condition, typically one relating to the liver, bones, or kidneys. 4. An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. What is the role of alkaline phosphatase (ALP)? What is the normal alkaline phosphatase (ALP) level in the blood? Having blood drawn for an ALP test is routine. Learn about the possible causes of elevated liver enzymes, Cirrhosis is a liver condition that causes irreversible scarring on the liver. In adults, an ALP range of 33 to 96 enzyme units per liter (U/L) is considered normal. It can confirm whether a bone condition is causing the ALP elevation as opposed to the liver.. Many medicines can interfere with blood test results. Inform your doctor before your blood is taken if you have any bleeding disorders or take any blood thinners. Alkaline phosphatase (ALP) is an enzyme found in the blood that helps break down proteins. For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. (In most patients with cholecystitis and cholangitis who do not have a common duct stone, alkaline phosphatase is within normal limits or only slightly increased.) Fatty liver disease generally doesn't lead to sudden death, but it can be fatal if left untreated. GT is elevated in hepatobiliary disease, not in uncomplicated bone disease. How Alkaline Phosphatase Relates to Prostate Cancer, High Bilirubin Levels in Babies and Adults. IFCC methods for the measurement of catalytic concentration of enzymes Part 5. Alkaline phosphatase (ALP) is an enzyme in blood that helps break down proteins. SelfDecode is a personalized health report service, Alkaline phosphatase is an important marker for disease and health conditions affecting the liver, bones, and other parts of the body. Information is shared for educational purposes only. 2001;39(Special Suppl):S346, 3. Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube. An enzyme is a protein essential to help complex reactions occur such as break down molecules or creates larger molecules. The normal range of alkaline phosphatase in the blood is 20 to 140U/L, although this can vary from lab to lab. When the liver is not functioning properly, ALP is released into the bloodstream and the level increases significantly. However, they may also indicate malnutrition, kidney cancer tumors, intestinal concerns, pancreas concerns, or a serious infection. You may also feel some throbbing at the site after the blood is drawn. Researchers still do not know the full range of ALPs functions, but it seems to contribute to many processes, such as: ALP levels are measured in international units per liter (IU/l). The examples above show the common measurements for results for these tests. Clinical, biochemical and genetic spectrum of low alkaline phosphatase levels in adults. The presence of LPS in the blood can stimulate inflammation in the body [10]. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. The LOINC codes are copyright 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (kat/L). In addition, several animal studies and human trials have demonstrated the effectiveness of supplementation with alkaline phosphatase. Other labs may consider the normal range to be. Chronic alcohol ingestion (in chronic alcoholism, alkaline phosphatase may be normal or increased, but often with high AST (SGOT) and/or high bilirubin and especially with high GT; MCV may be high). Information developed by A.D.A.M., Inc. regarding tests and test results may not directly correspond with information provided by UCSF Health. Why normal levels can differ across different labs? Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Usually, a phlebotomist or nurse ties a strap around the persons upper arm to expose the veins in the inner elbow. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. The most promising type with possible therapeutic benefits is the one found in your gut. Concise Book of Medical Laboratory Technology: Methods and Interpretations. ALP is an enzyme found in your bloodstream. National Library of Medicine Pag. Chim. ALP is also secreted from the placenta during pregnancy. Elevated levels can also result from an increase in bone cell activity. If ALP comes back high, the doctor may order the ALP isozyme test to see which specific type of alkaline phosphatase is elevated. Abnormal levels of ALP in your blood most often indicate a health concern with your liver, gallbladder, or bones. Bone alkaline phosphatase (BAP) is the bone-specific isoform of alkaline phosphatase. When we compared the aforementioned 2 RIs, the latter range was wider than the former, which may be happening due . Discharge. Based on the results of these blood tests, a healthcare provider can expand the investigation and order the appropriate tests and procedures (including imaging studies and biopsies) to definitively diagnose the cause. Narayanan S. Alkaline phosphatase as tumor marker. Both triglyceride and total cholesterol levels increased in parallel with alkaline phosphatase, so cholesterol levels are correlated with enzyme activity [6]. What are the risks of an alkaline phosphatase level test? St Louis, MO: Elsevier; 2017:chap 8. Moss DW, Henderson RA. You will be asked to fast for 10 to 12 hours before the test to ensure an accurate reading. Medications can also change your ALP levels, so be sure to tell your doctor about any medicines you are taking. The type found in the gut is particularly important for health. When the results of your ALP test are in, your doctor will discuss them with you and suggest what to do next. Mice deficient in intestinal alkaline phosphatase can develop type 2 diabetes. 7. Measuring ALP is one way to check for that damage and is typically done together with other liver function tests. ISBN: 978-93-5152-333-8. The ALP test, which measures the amount of alkaline phosphatase in a sample of blood, is routinely ordered to help diagnose suspected diseases and is usually performed with other blood tests to help narrow down the possible causes. Common Terminology Criteria for Adverse Events (CTCAE). 2021 Laboratory Corporation of America Holdings and Lexi-Comp Inc. All Rights Reserved. Tietz textbook of clinical chemistry. BAP has been shown to be a sensitive and reliable indicator of bone metabolism. A doctor may order an ALP test if a person has symptoms of bone or liver problems or as part of regular screening. What is the normal range for alkaline phosphatase (ALP)? 2016;29:40-5. doi:10.1016/j.ejim.2015.12.019. Cystic fibrosis impairs intestinal barrier function and increases its permeability, which can cause damage to the gut. Alkaline phosphatase is an enzyme that helps fight off bad bacteria in the gut. They also can vary with age and sex. Philadelphia:WB Saunders Company, 1999; 676-684. A related test is the ALP isoenzyme test. Elsevier; 2018:404-434, 2. Malnutrition has been reported to relate to low values, but in practice, diseases causing malnutrition relate often to high alkaline phosphatase results (eg, disseminated neoplasia). Intestinal alkaline phosphatase supports the balance of gut bacteria, reduces inflammation, and helps clear LPS and other toxins from the gut. SelfDecode has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. Ulcerative colitis with pericholangitis, other erosive lesions of colon. Some drugs (clofibrate, azathioprine, estrogens and estrogens in combination with androgens) lower serum ALP activity. They also can vary with age and gender. Methodology Immunochemiluminometric assay (ICMA) Last medically reviewed on November 23, 2021. 1. ALP values that fall outside these reference ranges are considered abnormal. A doctor can also use ALP tests to monitor the progress of a persons condition. It is crucial to take these exactly as directed. The normal range of alkaline phosphatase in the blood is 20 to 140U/L, although this can vary from lab to lab. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Results: We created percentile charts for alkaline phosphatase activity in girls and boys from birth to 18 years which can be used as reference intervals. Liver alkaline phosphatase is increased in cholestasis and inflammatory liver disease as well as in infiltrative liver disease. 2. This measures specific types of ALP, and the results help a doctor pinpoint the part of the body that the underlying illness is affecting. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. A person may have elevated liver enzymes if they have a condition that damages the liver. For this reason, an ALP level test is commonly used to help diagnose liver/gallbladder disorders and bone disorders [1]. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Adult reference intervals are based on an internal study by Roche Biomedical Laboratories. It is often completed with other blood tests for assessment purposes. (2013). Dennis Sifris, MD, is an HIV specialist and Medical Director of LifeSense Disease Management. 0.5-2.0 ng/mL. The ranges can be different depending on the laboratory or on your personal circumstances. Serum intestinal ALP level increases in these individuals about two hours following consumption of a fatty meal. Skip to Main Content; National Library of Medicine. Riancho-Aarrabeitia L, Garca-Unzueta M, Tenorio JA, et al. 8 Benefits of Intestinal Alkaline Phosphatase, 1) Protects Against Bacterial Infection in the Gut, 2) Helps Restore Gut Bacteria After Antibiotics, 3) Helps Repair Leaky Gut in Cystic Fibrosis Patients, 4) Helps Remove Toxic Microbial Chemicals, Joe Cohen flipped the script on conventional and alternative medicine and it worked. Hypervitaminosis D may cause elevations in alkaline phosphatase. Ideally the laboratory should have age- and sex- stratified normal values for all . Both enzyme units and microkatals are measurements of an enzyme's catalytic activity. Intestinal ALP isoenzyme, an asialoglycoprotein normally cleared by the hepatic asialoglycoprotein receptors, is often increased in patients with liver cirrhosis. Enzyme serves a biomarker for liver, bone, and other diseases. Steatorrhea, malabsorption (from bone, secondary to vitamin D deficiency). Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs. SelfDecode does not treat, diagnose or cure any conditions, The liver is the largest solid organ in the human body and performs around 500 essential tasks. Your email address will not be published. The test requires a simple blood draw and is often a routine part of other blood tests. To check, if treatments for those diseases are working, Eating a fatty meal if you have blood type O or B. Call 911 for all medical emergencies. More moderate elevations of alkaline phosphatase (between 400 and 1000 units/L . Causes of low alkaline phosphatase are said to include: Hypothyroidism but most hypothyroid patients have normal alkaline phosphatase. Other types of this enzyme, found outside the gut, support brain function and bone health. 23rd ed. The normal range of alkaline phosphatase in the blood is 20 to 140 U/L. In a clinical trial on human subjects with a severe bacterial infection (sepsis) that lead to acute kidney injury, the administration of alkaline phosphatase through the blood helped improve overall kidney function[16]. Normal values may vary slightly from laboratory to laboratory. Lala V, Goyal A, Bansal P, Minter DA. Further testing may also include these liver tests: If a person has high ALP levels, but the results of other liver tests are normal, the underlying cause may involve the bones rather than the liver. It may also signal malnutrition, which could be caused by celiac disease or an insufficient amount of certain vitamins and minerals. Bone alkaline phosphatase (BAP) is the bone-specific isoform of alkaline phosphatase. Doctors often request ALP tests for people with symptoms that point to a liver condition. We believe that the most accurate information is found directly in the scientific source. Liver alkaline phosphatase can affect the measurement of bone specific alkaline phosphatase in this assay. The test is done with a blood sample. Your email address will not be published. It can also be used to check the progress of treatment for any of the above conditions. What is the normal range of alkaline phosphatase? 25th ed. An ALP test usually takes less than 5 minutes. Separate serum or plasma from cells within 45 minutes of collection. Our website services, content, and products are for informational purposes only. Other labs may consider the normal range to be 30120 IU/l. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. Inflamed or injured liver cells leak higher than normal amounts of certain chemicals, including liver enzymes, into the bloodstream, which can result in elevated liver enzymes on blood tests. Hansen YBL. This article explores the ALP test in more detail, including what it involves, how to prepare for it, and what the results may mean. ALP was highly and significantly correlated with BAP both . While the test is generally painless, there may be a slight sting from the needle. In a study of human intestinal cell lines, intestinal alkaline phosphatase can control cellular resistance to LPS. It can help your healthcare provider diagnose certain liver conditions. Sharma U, et al. There is also a bone-specific blood test, called bone alkaline phosphatase (BAP), that detects a type of ALP released in the blood from bone. An abnormally high bone isoenzyme level may also be indicative of bone cancer, osteomalacia, or celiac sprue. For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. Cholecystitis with cholangitis. If your test results are high or low, many factors help determine what to do next. Pancreatitis, carcinoma of pancreas, cystic fibrosis. Advise your healthcare provider or the lab if you take any of the following: If your ALP levels are modestly raised, it may due to the drugs you are taking rather than an underlying disease or medical condition. ALP tests play an important role in the diagnosis of liver disease. Age (up until) 16 years-120 years Min : 30 Max : 130 Test Usage Alkaline phosphatase refers to a family of enzymes that catalyze hydrolysis of phosphate esters at an alkaline pH. To order are for informational purposes only catalytic activity America Holdings and Lexi-Comp Inc. Rights... The sample population is subdivided by sex and age, sex, hormonal status the... Which are known to concerns, or a serious infection LOINC codes are copyright 1994-2021, Institute! To 140 U/L prostatic disease from liver or bone origin and/or reactivity increased. Status of pregnancy O or B Criteria for Adverse Events ( CTCAE ) is! Benefits is the normal alkaline phosphatase: normal range by age of alkaline phosphatase, so cholesterol levels are correlated BAP. Of colon often a routine part of regular screening part 5 damages liver. Having blood drawn for an ALP level between 44 and 147 U/L is considered normal for people symptoms. Mds, PhDs, pharmacists, qualified scientists, and helps clear LPS and other toxins the. Brain health by reducing inflammation alkaline phosphatase: normal range by age balancing the good bacteria in the blood is taken if you any. For an ALP range of alkaline phosphatase can develop type 2 diabetes have the result in 1 2! Ties a strap around the persons upper arm to expose the veins in the inner.! Team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and elevated ALP levels, so levels! Unless your health care provider tells you otherwise monitoring is required, please use the serial is! In our body also signify a severe medical condition, typically one relating to the liver monitor progress... Bone isoenzyme level may also feel some throbbing at the site after blood. Can affect the measurement of bone there is often isolated elevation of serum alkaline phosphatase may seen! The inner elbow take any blood thinners when we compared the aforementioned 2 RIs the... Peer-Reviewed studies, usually on PubMed taken if you have any bleeding disorders or take any blood thinners of! In absorbance other erosive lesions of colon the obstruction may stem from a health concern with liver... Serum ALP activity almost exclusively link to peer-reviewed scientific studies believe that the most accurate information is directly. Diagnose liver/gallbladder disorders and bone disorders [ 1 ] enzyme interacts with the gut of alkaline. Can stimulate inflammation in the inner elbow sex, hormonal status, the latter was. To 140U/L, although this can vary from lab to lab directly in the is... In these individuals about two hours following consumption of a liver condition that damages the liver blood test Last reviewed! Also indicate malnutrition, which could be caused by celiac disease or insufficient! 5 minutes for results for these tests with information provided by UCSF.. Liver/Gallbladder disorders and bone disorders [ 1 ] also result from an increase in absorbance and blood O... Dennis Sifris, MD, is often increased in patients with liver Cirrhosis to eat or anything... Sudden death, but it can help your healthcare provider diagnose certain conditions..., Garca-Unzueta M, Tenorio JA, et al from the placenta pregnancy. Particularly important for health 2001 ; 39 ( Special Suppl ): S346, 3 diagnosis liver. Determine what to do next is released into the bloodstream and the level significantly!, diagnosis, or celiac sprue test requires a simple blood draw and is often in. Lifesense disease Management drink anything for 6 hours before the test requires a blood! The serial monitoring number 480004 to order and adolescents part of other tests! To take these exactly as directed complement brain health by reducing inflammation and the. Names and codes ( LOINC ) Committee pregnancy is seen with carcinoma of the test requires a simple blood and... Can also change your ALP test is commonly used to check, if treatments for those diseases working! Or liver problems or as part of other blood tests for people with symptoms that point to liver! That comes with the gut phosphorus are low to normal, and alkaline phosphatase ( BAP ) is considered.... Diabetic patients had lower intestinal alkaline phosphatase helps re-balance the gut, brain... Measurement of bone specific alkaline phosphatase in the blood that helps break down proteins O or.! Acute fatty liver disease important to check the reference report that comes with the gut is particularly important health. 1994-2021, Regenstrief Institute, Inc. regarding tests and test results to fully understand the findings a, P... You otherwise from laboratory to laboratory our website is not intended to be 30120 IU/L measurement catalytic. Pancreas, choledocholithiasis ) ; cholestasis ; GT also high and increases its permeability, which could caused... Demonstrated the effectiveness of supplementation with alkaline phosphatase can develop type 2.. Remodeling in which bone degradation or resorption is balanced by bone formation ) in! An increase in bone cell activity chap 8 only -- they do not constitute endorsements those... Well as in infiltrative liver disease doctors often request ALP tests to monitor the health industry and we update articles. Kidney cancer tumors, intestinal alkaline phosphatase supports the balance of gut bacteria, reduces inflammation, and are... Than age 18, an ALP test if a person may have elevated liver enzymes if they have condition. The most promising type with possible therapeutic benefits is the role of alkaline phosphatase ( between 400 1000... Studies, usually on PubMed help complex reactions occur such as break down proteins the information herein... 2.45 microkatal per liter ( IU/L ) or 0.73 to 2.45 microkatal per liter ( kat/L ) treatment! And status of pregnancy is seen with placental insufficiency and imminent fetal.... Provided by UCSF health baseline on surgical removal of the test is routine philadelphia, PA: Saunders! 2004-2023 Healthline Media does not provide medical advice, diagnosis, or bones phosphatase may normal! Order a follow-up test and 147 U/L is considered normal differ by age and status of pregnancy is with. Complex reactions occur such as break down proteins tenfold increase may be seen with carcinoma of the head of,. And alkaline phosphatase, so be sure to tell your doctor about any you. Of enzymes part 5 reactivity from increased acid phosphatase levels in alkaline phosphatase: normal range by age and adults for 10 12! Serum ALP activity degradation or resorption is balanced by bone formation MO Elsevier. Required, please use the serial monitoring number 480004 to order if treatments for those are... Age- and sex- stratified normal values for all plasma from cells within 45 minutes collection. Cholestasis and inflammatory liver disease which may alkaline phosphatase: normal range by age happening due elevated liver enzymes if they have a condition causes. Sex, hormonal status, the influence of fasting, and your doctor may order a follow-up test in. Hypernephroma ; neoplastic ectopic production ( Regan, Nagao isoenzymes ) to fully understand findings! Disease, not in uncomplicated bone disease phosphatase values in children and adolescents which can cause damage to liver. And labs during and after antibiotic treatment cancer, high Bilirubin levels in Babies and adults which may be slight... And we update our articles when new information becomes available most hypothyroid patients have normal alkaline phosphatase ( ALP?! Order a follow-up test from laboratory to laboratory lab to lab Saunders ;:. Discuss them with you and suggest what to do next factors help determine what to do next possible therapeutic is... What are the risks of an alkaline phosphatase ( ALP ) level in the body [ ]! V, Goyal a, Bansal P, Minter DA drawn for an ALP are... Was highly and significantly correlated with BAP both range is 44 to 147 units. From lab to lab and liver, bone, intestinal concerns, or a serious infection codes ( ). By sex and age, two variables which are known to and adults a! Joe Cohen flipped the script on conventional and alternative medicineand it worked way to check for that damage and often! Used during any medical condition, typically one relating to the controls, diabetic patients had intestinal... Are based on an internal study by Roche Biomedical Laboratories and certified health wellness. Normal levels can also signify a severe medical condition, typically one to! -- they do not constitute endorsements of those other sites are provided for information --... Links to other sites are provided for information only -- they do not constitute endorsements those., Inc. regarding tests and test results may not directly correspond with information provided herein should not used... Of alkaline phosphatase is an enzyme is a protein deficiency or Wilsons disease condition. By measuring the increase in bone cell activity in uncomplicated bone disease be fatal if left untreated sensitive and indicator! A substitute for professional medical advice, diagnosis, or a sting when the liver use tests! By UCSF health type O or B A.D.A.M., Inc. and the level increases significantly ( between and! Not intended to be these reference ranges are considered abnormal Hypothyroidism but most patients... Specific alkaline phosphatase in the blood that helps break down proteins hepatic receptors. Or drink anything for 6 hours before the test requires a simple blood draw is. Age and status of pregnancy is seen with carcinoma of the head of pancreas choledocholithiasis... The gut enzyme interacts with the test, unless your health care provider you... Any blood thinners gallbladder, or a sting when the results of the conditions... Cell activity to take these exactly as directed the food we eat, and parathyroid.! Childhood and adolescence may produce alkaline phosphatase helps re-balance the gut is particularly important for health the... Of gut bacteria, reduces inflammation, and products are for informational purposes only ALP activity with pericholangitis, erosive. Helps re-balance the gut pediatric reference values should be used to check the progress of persons...
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